(5S,6R)-6-Bromo-6-methyl-5-phenyl-3,4,5,6-tetrahydro-2H-cyclopenta[b]pyran-7-one
نویسندگان
چکیده
The title compound, C(15)H(15)BrO(2), was synthesized by a Brønsted acid-catalysed domino electrocyclization-halogenation reaction. The five-membered ring is essentially planar (r.m.s. deviation 0.006 Å) and forms a dihedral angle of 72.7 (3)° with the attached phenyl ring. The six-membered heterocycle adopts a half-chair conformation. The crystal packing is stabilized by a C-H⋯O contact.
منابع مشابه
3,5-Dimethyl-2,6-diphenyl-3,4,5,6-tetrahydro-2H-pyran-4-one
The mol-ecular structure of the title compound, C(19)H(20)O(2), reveals a slightly distorted chair conformation for the tetra-hydro-pyran ring with the two methyl and two phenyl substituents in equatorial positions.
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In the title compound, C15H18N2O5, the meth-oxy-phenyl ring makes a dihedral angle of 84.70 (12)° with the mean plane of the tetra-hydro-pyrimidin-2(1H)-one ring. Both the pyran and tetra-hydro-pyrimidin-2(1H)-one rings have distorted envelope conformations with the carboxyl-ate-substituted C atom as the flap. In the crystal, mol-ecules are linked via pairs of N-H⋯O hydrogen bonds, forming zigz...
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